2023 NFL Week 1 Odds, Predictions: Picks, lines, spreads for every game

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The 2023 NFL schedule is here! In the season opener, the defending Super Bowl champion Kansas City Chiefs open at home against the Detroit Lions on Thursday, September 7th.

The Chiefs are the current favorites to win Super Bowl LVIII, +600 at FOX Bet. The champions’ first test will be against a Detroit team that showed strength during the 2022 season. Kansas City is currently favored by 6.5 points in this exciting season opener.

On a side note, here’s a fun nugget you can share with your friends about the Chiefs. They are currently the only team favored in all their matches in 2023.

Sunday, September 10th is the first Sunday of the regular season, and fans and bettors can watch some of the most exciting games of the day on FOX and the FOX Sports app.

The Carolina Panthers open at the Atlanta Falcons in an NFC South matchup, a game where No. 1 overall pick Bryce Young will likely make his NFL debut. The Falcons are favorites with 2.5 points in this matchup.

Another big game on FOX features the San Francisco 49ers taking on the Pittsburgh Steelers. San Francisco is currently favored by 3 points in this first game. The 49ers are also the fourth favorite at FOX Bet at +800 to win it all next season.

The afternoon card features a rivalry as old as time, with Justin Fields and the Chicago bones assuming Jordan Love and the Green Bay Packers. Chicago is currently favored against Green Bay, a rarity if you look back at the last few years with quarterback Aaron Rodgers at the helm.

Speaking of Rodgers, Monday night’s game will feature the new-look New York Jets as they take the field with him at quarterback. The Jets currently have the seventh best odds (+1600) to win next season’s Lombardi. One thing is for sure, see A’s mission. Rod to lead his new team to the Super Bowl will be must-see TV all season long.

Also, if you’re looking for some help on how to spend a couple bucks on season openers, we’ve got a couple of the best early bets from FOX Sports NFL Betting Analyst Geoff Schwartz!

So let’s dive into the lines for each opening weekend game.

Here are the 2023 NFL Week 1 lines for each game (via FOX Bet):

Detroit Lions +6.5 at Kansas City Chiefs
San Francisco 49ers -3 at Pittsburgh Steelers
Carolina Panthers +2.5 at Atlanta Falcons
Houston Texans +9.5 at Baltimore Ravens
Cincinnati Bengals -2.5 at Cleveland Browns
Oakland Raiders +3.5 at Denver Broncos
Tampa Bay Buccaneers +6 to Minnesota Vikings
Arizona Cardinals +6 to Washington Commanders
Tennessee Titans +4 at New Orleans Saints
Jacksonville Jaguars -4 at Indianapolis Colts
Los Angeles Rams +4.5 at Seattle Seahawks
Philadelphia Eagles -4 at New England Patriots
Green Bay Packers +1.5 at Chicago Bears
Miami Dolphins +2 to Los Angeles Chargers
Dallas Cowboys -2.5 at New York Giants
Buffalo Bills -2 at New York Jets

Giants vs Eagles on Christmas Day, 49ers vs Eagles in Week 13 announced ahead of NFL schedule release

Giants vs Eagles on Christmas Day, 49ers vs Eagles in Week 13 announced ahead of NFL schedule release

Kevin Burkhardt and Erin Andrews announced two big matchups for FOX NFL this season.

A few other notable matchups stand out on the Week 1 card. Here’s a quick look.

Buffalo Bills -2 at New York Jets

Josh Allen and the Bills are currently two-point favorites in their opener against the Jets. They also come into the season with high expectations, according to the odds of winning the Super Bowl at +800.

Buffalo lost 27-10 to Cincinnati in the divisional round last season and will focus on making an even deeper playoff run. Allen finished the year with 4,283 passing yards and 35 touchdowns.

Can Allen outmatch Rodgers in this first All-Star game?

Philadelphia Eagles -4 at New England Patriots

The Eagles at the Patriots will be another game to mark the opening week calendars. The Eagles flew high last year with a fantastic run to the Super Bowl. Unfortunately, his career ended in a 38-35 loss to the Chiefs, but Philadelphia has a chance to get back to the big game after having one of the best drafts. The team loaded up its defense, supplementing its already impressive unit with several players from one of the all-time best defensive units made up of Georgia players.

The franchise also agreed to terms with superstar QB Jalen Hurts to the tune of $255 million, ensuring the most important position in football is locked up for them for years to come.

The Aaron Rodgers effect gives the Jets five prime-time games in 2023

The Aaron Rodgers effect gives the Jets five prime-time games in 2023

The NFL schedule is out, which means the season is right around the corner!

Dallas Cowboys -2.5 at New York Giants

Can the Cowboys finally make a deep playoff run worth mentioning? Or is Dallas doomed to exit the playoffs in the divisional round again, or worse, the Wild Card round?

The boys are 2.5 favorites over NFC East foe New York in Week 1. A Week 1 win in enemy territory could be just what Team USA needs to silence doubters and boost confidence of quarterback Dak Prescott as the season begins.

Miami Dolphins +2 to Los Angeles Chargers

Dolphins at Chargers will be another fun contest to watch with two high flying offenses. This will be a battle between Tua Tagovailoa, a quarterback whose season was plagued by injuries in 2022, and Justin Herbert, a player that FOX sports betting analyst Sammy P likes to win MVP.

The Chargers are currently favored by 2 in this matchup.

Brian Daboll won’t talk about Saquon Barkley’s contract

Brian Daboll won't talk about Saquon Barkley's contract

Craig Carton joins Greg Jennings to talk about the biggest headlines in football, including the New York Giants head coach refusing to talk about Saquon Barkley’s contract.

FOX Sports NFL Betting Analyst Expert Picks Geoff Schwartz:

With the NFL schedule set, it’s time to look at some Week 1 NFL betting lines because it’s never too early to start thinking about the upcoming season. Here are a couple of the best bets that piqued my interest at first glance:

San Francisco 49ers at Pittsburgh Steelers (+3 at FOX Bet)

The Steelers have won three straight opening weekend games, including two upsets on the road. In 2021, they traveled to Buffalo and stunned the Bills, winning 23-16. Last year, they opened the year forcing five turnovers in a win at Cincinnati. Pittsburgh coach Mike Tomlin always has his team ready for the season opener.

This year they have a top defense, good position players on offense and quarterback Kenny Pickett in his second year. Pickett showed enough flash late last season to show he has the potential to live up to his draft spot.

I have never seen a team built like the 49ers in my life. The 49ers can lay claim to having the best running back, left tackle, pass rusher and receiver in the league. Throw in Deebo Samuel as an elite offensive weapon, plus young secondary pieces, and this is the best roster in the league. hands down

However, they are average at quarterback and currently have Sam Darnold making first-team reps in the offseason. Trey Lance, SF’s No. 3 pick in the 2021 draft, has started four games in two seasons and is recovering from multiple lower leg surgeries. Seventh-round rookie sensation Brock Purdy is recovering from elbow surgery. The 49ers don’t have great quarterback options right now. That’s why I’m going with the Steelers to cover Week 1: Too much uncertainty at quarterback in San Francisco.

COLLECT: Pittsburgh (+3 at FOX Bet at time of pick) to lose by less than 3 points (or win outright)

Philadelphia Eagles at New England Patriots (+5 at FOX Bet)

The Eagles are legitimate favorites to win the NFC again in 2023, but I’ll be fading them in Week 1 against the Patriots. The Super Bowl hangover is real, especially when the Super Bowl runners-up open as favorites. Even when those teams have won, like the 2017 Falcons, they didn’t cover the game.

While the Patriots haven’t been as strong without Tom Brady, their outstanding defense has continued to play well. They finished best in the league in weighted defensive DVOA last season, and I expect the same effort this season. This unit will be ready, with coach Belichick having months to prepare.

On offense, the Patriots hired former Texans head coach and Alabama offensive coordinator Bill O’Brien to run the show. This is a massive upgrade from what the Patriots tried to do last season. He was a poor GM, so he gets mocked for his time in Houston, but he keeps goingfield performance was good. The Texans won the division in four of his six seasons, while his time at Alabama saw quarterback Bryce Young win the Heisman Trophy.

The Patriots will have a functional offense this season. There are question marks at wide receiver, which could slow them down, but I still like his chances to cover the five in Week 1.

COLLECT: Patriots (+5 on FOX Bet at time of pick) to lose by less than 5 points (or win outright)

Stay tuned to FOX Sports to keep up with the odds as they progress in NFL Week 1!

Download the FOX Super 6 app for a chance to win thousands of dollars on the biggest sporting events every week! Just choose your picks and you could win the grand prize. Download and play today!

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