College football odds Week 10: How to bet Ohio State-Northwestern

The Ohio State Buckeyes take on the Northwestern Wildcats in a battle of Big Ten teams in Week 10 of the college football season.

Unbeaten Ohio State enters this game after defeating rival Penn State in Happy Valley 44-31 in Week 9. On the other hand, Northwestern enters this game on a seven-game losing streak. The Wildcats’ only win came in Week 1 against Nebraska.

Will the Wildcats pull off the upset at home in Week 10, or will the Buckeyes keep their perfect season intact and improve to nine wins on the season?

Here’s everything you need from a betting perspective on the Ohio State vs. Northwestern game, from point spread, money line, Over/Under total and expert pick Bet FOX).

No. 2 Ohio State at Northwest (Noon ET Saturday, ABC)

Distribution of points: Ohio State -38 (Ohio State is favored to win by 38+ points, otherwise Northwestern covers)
Moneyline: N/A
Total Over/Under Score: 57.5 points scored by both teams together


Ohio State Buckeyes


Wildcats of the Northwest


Pick through the FOX sports betting analyst Jason McIntyre:

The Wildcats haven’t beaten Ohio State since 2004, and that’s not happening here.

Yes, it’s the Buckeyes’ second straight road game, but the Wildcats haven’t won since beating Nebraska in the season opener in Ireland. The last time Northwestern won a football game in America was Oct. 16 against Rutgers in 2021. That was over a calendar year ago.

The Buckeyes will put up some stats for Heisman candidates, avoid injuries and win big. Don’t be afraid to put the points.

TO PICK UP: Ohio State (-38 at FOX Bet) to win by 38+ points

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