NFL wild-card odds: How to bet Seahawks-49ers

The hottest team in the NFL will face a team that needed help to clinch the final playoff spot in the NFC when the San Francisco 49ers (13-4) host the Seattle Seahawks (9-8) on Saturday in a Wild Card Weekend matchup of NFC West Division Rivals.

The 49ers are on a 10-game winning streak, while the Seahawks lost five of six games before winning their last two contests and, with a big assist from the Detroit Lions beating the Green Bay Packers, clinched the spot NFC playoff final.

But the Seahawks have an edge, as they lead the all-time series 30-19, even though the 49ers swept both regular-season contests 27-7 and 21-13.

Here’s everything you need from a betting perspective on the Seahawks-49ers game, from point spread, money line, Over/Under total and expert pick (odds via FOX Bet ):

Brock Purdy on Niners’ confidence to finish regular season strong

Brock Purdy on Niners' confidence to finish regular season strong

San Francisco quarterback Brock Purdy on teams’ confidence heading into the playoffs.

RELATED: Lines for Wild Card Weekend

Seattle Seahawks at San Francisco 49ers (4:30 p.m. ET Saturday, FOX and FOX Sports app)

Distribution of points: 49ers -10 (49ers favored to win by 10+ points, otherwise Seahawks cover)
Moneyline: 49ers -500 favorites to win (bet $10 to win $12 total); Seahawks +300 underdogs to win (bet $10 to win $40 total)
Total Over/Under Score: 42.5 points scored by the two teams together

Pick through the FOX sports betting analyst Jason McIntyre:

They’ve met twice this season, with the 49ers outscoring both games by a combined 48-20.

Seattle only got into the red zone twice against the 49ers defense. Seattle was fortunate to sneak into the playoffs as Geno Smith didn’t play well down the stretch, with multiple interception games at home against the Rams and Panthers. This will be his first playoff start (same for the 49ers’ Brock Purdy), but you have to give huge credit to the 49ers’ offense, which crushed Seattle by 6.2 yards per play last month in Seattle. And that was without Deebo Samuel (he’s back).

The Seahawks struggle to defend tight ends (George Kittle had two TDs in the last meeting) and will also be without their leading tackler Jordyn Brooks, the 2020 first-round pick who is out for the season.

Seattle’s way to keep it close is to maybe attack Purdy a lot and expect him to make mistakes, then deploy a chain-moving offense with Tyler Lockett (16 catches for 175 yards in two meetings) and then pray that Kenneth Walker can find space against the NFL’s No. 2 rushing defense.

If you have to bet the 49ers here, just know you’re paying a premium, as they’re riding a 10-game winning streak and have covered seven of eight. Since 2001, teams entering the playoffs with a 10+ game streak are 2-13 against the spread.

COLLECT: 49ers (-10 at FOX Bet) to win by more than 10 points

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